Women in Science: Simone Niclou, oncologist

 

January 2017

Early in 2017, a small exhibition in Luxembourg City highlighted a selection of ‘WiSE – Women in Science and Engineering’. Here we introduce one of the featured scientists, LIH’s Simone Niclou, oncologist and coordinator of CANBIO, one of the 11 Doctoral Training Units funded through the FNR’s PRIDE programme.

In addition to coordinating a PRIDE DTU, Simone Niclou, PhD, heads up the Norlux Neuro-Oncology Laboratory at the Luxembourg Institute of Health (LIH), where she is also Head of the Animal Facility. Her field of expertise includes the biology of malignant brain tumours with a focus on angiogenesis, invasion, tumour metabolism and tumour heterogeneity.

She is a frequently invited speaker at various international scientific conferences, in addition to being a guest lecturer at national and international universities. She has also been the President of the Board of Directors of the Laboratoire National de Santé since 2015.

Research goals: Improving options for brain cancer patients

Simone Niclou’s research revolves around brain cancer. Her goal is to improve treatment and extend the life expectancy of patients.

With Glioblastomas – the most dangerous and common type of brain tumour – the life expectancy of the patients is only around one year, and there are but few treatment options. The goal of the research of Simone Niclou’s working group is to develop new therapies and medications, as much as it is to understand how brain cancer starts.

But Simone Niclou no longer conducts lab experiments – she leads a research group and is the coordinator of CANBIO, one of the 11 Doctoral Training Units funded through the first Call of the FNR’s PRIDE programme.

CANBIO stands for a Luxembourg Institute of Health (LIH) PhD training programme by the name of ‘Training in Cancer Biology: Focus on tumour escape mechanisms’. It addresses the clinical problem of tumour progression and recurrence. The PhD candidates on this programme will be involved in a a collaborative and interdisciplinary effort to deliver novel insight into tumour escape mechanisms, disease monitoring and large scale data analysis in highly malignant cancers.

Find out more about CANBIO on the LIH’s website.

WiSE women exhibition

Find out more about the WiSE women exhibition (20 January to 11 February 2017, Luxembourg City)

Simone Niclou, oncologist at the Luxembourg Institute of Health

MEET THE SCIENTISTS: SIMONE NICLOU

RELATED PROGRAMMES

RELATED HIGHLIGHTS

FNR ATTRACT Fellows – the people behind the science: Emma Schymanski

Emma Schymanski is a chemist and environmental engineer, who embarked on her FNR ATTRACT Fellowship in 2018. Her husband Stan Schymanski is also an FNR ATTRACT Fellow, making them the first dual career couple to both benefit from this scheme. We spoke to Emma about her group’s detective work to find traces of chemicals in our environment and the associated challenges; her experiences as a woman in STEM; open science, and the experience of setting up your own research group for the first time.

Spotlight on Young Researchers: Environmental factors and their role in Parkinson’s Disease

An estimated 10% of Parkinson’s Diseases cases are due to genetic factors – in the search for answers as to what could cause the other 90%, research is increasingly finding evidence pointing to environmental factors. To paint a clearer picture of what role chemicals could play in the disease, researchers are for example looking for ‘fingerprints’ of chemicals in biological samples.

Spotlight on Young Researchers: Collecting individual and personal stories of the war generation in Luxembourg

Over 10,000 Luxembourgish women and men wore German uniforms during WWII in armed forces and civil organisations – many were drafted by the Nazi German authorities – and behind each name is a story waiting to be told. A team of researchers has been working with families in Luxembourg to piece together the personal stories of the war generation in Luxembourg.

Spotlight on Young Researchers: The human gut microbiome and the clues it holds

Research is steadily painting a picture revealing the significance the human gut microbiome plays in health and disease. From gastrointestinal tract disorders to the beginnings and treatment of Parkinson’s disease and beyond, the gut microbiome is a treasure trove of clues for researchers. We speak to three women in science – a biomedical scientist, a microbiologist and a bioscience engineer – about organs-on-chips and restoring an imbalanced microbiome.

Spotlight on Young Researchers: Nature’s shapes as mathematical challenges

In nature, we see hyperbolic forms in corals, flatworms, and many other species of reef organisms, such as sponges and kelps. The hyperbolic spaces are also of interest for mathematicians, who are looking to prove the solvability of invariant systems of differential equations in unusual spaces such as these.

Spotlight on Young Researchers: Dementia in neurodegeneration – defining the role of microglia, the brain’s immune cells

An estimated 55 million people in the world suffer from dementia, with the number estimated to increase to 78 million by 2030. In Luxembourg, more than 10,000 people suffer from dementia, including patients affected by Alzheimer’s disease and Dementia with Lewy Bodies. These incurable diseases have an increasing socio-economic impact along with the burden on patients and caregivers. One of the approaches researchers are taking is studying microglia, immune cells in the brain.

Spotlight on Young Researchers: Measuring the environmental impact of investment funds

Sustainable capital market investments are expected to reach 53 trillion USD – about 1 in every 3 dollars invested – by 2025. Meanwhile, a much lower level of funds are going directly into climate-related projects, leading to an increasing concern of greenwashing in the market. Researchers are developing science-based tools to measure the environmental impact of financial investment decisions.

Be brave: Women [& girls] in Science: Denisa Naidin

“You can do whatever you set your mind to! Your unique skillset can produce life-changing innovations, encourage research teams towards exploration, inspire others and help society evolve towards more equality, diversity and openness.”, says Denisa Naidin besides being a PhD researcher in economic geography is also a passionate photographer, trekker, mother and more. Discover more in the final video in the Be brave: Women [& girls] in Science series.

Be brave: Women [& girls] in Science: Elisabeth John

“The enthusiasm and understanding for research starts with the youngest members of our society”, says Elisabeth John who after completing her PhD, built up the Scienteens Lab at the University of Luxembourg, which now receives 2,000 young people per year, showing them a possible career path in science, and throw experiments shows them the importance of making fact-based decisions.

Be Brave: Women [& girls] in Science: Emmanuella Osuebi-Iyke

“You don’t need to have it all figured out. Just take that leap.” The fourth video in the series Be Brave: Women [& girls] in Science is Emmanuella Onyinyechi Osuebi-Iyke, whose curiosity for how plants function led her to a research career in Plant / Environmental Science.

This site uses cookies. By continuing to use this site, you agree to the use of cookies for analytics purposes. Find out more in our Privacy Statement